115533-10G CDI Sigma Reagent grade

DESCRIPTION
General description
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. 1,1′-carbonyldiimidazole (CDI) is an alternative to highly toxic insidious poison phosgene and thus aligns with the principle "Designing Safer Chemicals". For more information see the article Controlled Synthesis of Asymmetric Dialkyl and Cyclic Carbonates Using the Highly Selective Reactions of Imidazole Carboxylic Esters.
Application
Coupling agent in the synthesis of dipolar polyamides for nonlinear optical applications[1] and polypeptides.[2] Also used to make β-keto sulfones and sulfoxides,[3] lead sequestering agents,[4] and β-enamino acid derivatives.[5]

SAFETY INFORMATION
Pictograms
CorrosionExclamation markHealth hazard
GHS05,GHS07,GHS08
Signal Word
Danger

Hazard Statements
H302 - H314 - H360D
Precautionary Statements
P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1B

Storage Class Code
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK
WGK 2

Flash Point(F)
Not applicable

Flash Point(C)
Not applicable

Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves

Synonym(s):
1,1′-Carbonyldiimidazole
Empirical Formula (Hill Notation):
C7H6N4O

PROPERTIES
grade
reagent grade

Quality Level
200

Assay
≥90.0% (proton, NMR)

form
solid

reaction suitability
reaction type: Carbonylations

greener alternative product characteristics
Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.

mp
117-122 °C (lit.)

application(s)
peptide synthesis

greener alternative category
Aligned

SMILES string
O=C(n1ccnc1)n2ccnc2

InChI
1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H

InChI key
PFKFTWBEEFSNDU-UHFFFAOYSA-N